Archives For salivary gland cancer

“During the last years increasing evidence implies that human cytomegalovirus (CMV) can be attributed to human malignancies arising from numerous tissues. In this perspective, we will review and discuss the potential mechanisms through which CMV infection may contribute to brain tumors by affecting tumor cell initiation, progression and metastasis formation. Recent evidence also suggests that anti-CMV treatment results in impaired tumor growth of CMV positive xenografts in animal models and potentially increased survival in CMV positive glioblastoma patients. Based on these observations and the high tumor promoting capacity of this virus, the classical and novel antiviral therapies against CMV should be revisited as they may represent a great promise for halting tumor progression and lower cancer deaths.”

CMV In Human Brain Tumors – World Journal Experimental Medicine

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iStock_000011406696Small“Typically, this pathway is only active during embryonic growth and development,” Melnick said, “but when CMV turns it back on, the resulting growth is a malignant tumor that supports production of more and more of the virus.”

http://dentistry.usc.edu/2011/11/14/common-virus-conclusively-identified-as-cancer-causing-oncovirus-ostrow-school-of-dentistry-researchers-pinpoint-cytomegalovirus’-central-role-in-salivary-gland-cancer/