“During the last years increasing evidence implies that human cytomegalovirus (CMV) can be attributed to human malignancies arising from numerous tissues. In this perspective, we will review and discuss the potential mechanisms through which CMV infection may contribute to brain tumors by affecting tumor cell initiation, progression and metastasis formation. Recent evidence also suggests that anti-CMV treatment results in impaired tumor growth of CMV positive xenografts in animal models and potentially increased survival in CMV positive glioblastoma patients. Based on these observations and the high tumor promoting capacity of this virus, the classical and novel antiviral therapies against CMV should be revisited as they may represent a great promise for halting tumor progression and lower cancer deaths.”
Archives For Rhabdomyosarcoma
I’ve written often about the fact that 99% of Glioblastoma and 92% of Medulloblastoma show active CMV infections and show signs that CMV has hit and run certain tumor cells making genetic and epigenetic changes.
Now researchers are testing Neuroblastoma for CMV and the latest research shows 100% of the tumors showed signs of CMV or cyclomegalovirus. This continues to reinforce that brain cancers key consistent factor is the triggering of oncogenisis is by a viral infection that over expresses oncogenes and disables key anti-oncogenes thus driving these devastating cancers and leads towards potential opportunities for new and less devastating treatment options including using anti-virals like Valcyte.