“During the last years increasing evidence implies that human cytomegalovirus (CMV) can be attributed to human malignancies arising from numerous tissues. In this perspective, we will review and discuss the potential mechanisms through which CMV infection may contribute to brain tumors by affecting tumor cell initiation, progression and metastasis formation. Recent evidence also suggests that anti-CMV treatment results in impaired tumor growth of CMV positive xenografts in animal models and potentially increased survival in CMV positive glioblastoma patients. Based on these observations and the high tumor promoting capacity of this virus, the classical and novel antiviral therapies against CMV should be revisited as they may represent a great promise for halting tumor progression and lower cancer deaths.”
Archives For oncogenic
Many factors contribute to Cancer, but the key catalyst (even the underlying engine) is one of many Viruses, particularly CMV, but also VZV, Epstein Barr as well as other Viruses SV-40, BK, JCV and HPV. Each cancer in our body has one to many viruses associated with it. Some key ones are HPV – Human Papilloma Virus causes Cervical, Anal, Mouth, Throat, Lung, Vaginal and Penile Cancers. Epstein Barr causes Lymphoma, JC Polyoma Virus causes Colon Cancer. Epstein Barr, HPV & CMV have all been associated with Breast Cancer, thus one reason for it’s prevalence. Now down to kids Cancer, Medulloblastoma Neuroblastoma and it’s 99% terminal twin cancer Glioblastoma. For these cancers its mainly CMV (Human Cytomegalovirus), though other viruses like SV-40, JC and BK are also capable and have been found in these tumors.
Brain cancers and head and neck cancers together account for more than 873,000 cases annually worldwide, with an increasing incidence each year.
A major problem with such research is that the role of many infectious agents may be underestimated due to the lack of or inconsistency in experimental data obtained globally.
Our analysis of the literature showed the presence of human cytomegalovirus (HCMV) in distinct types of brain tumour, namely glioblastoma multiforme (GBM) and medulloblastoma. In particular, there are reports of viral protein in up to 100% of GBM specimens.
Hit & Run – An active viral infection, rewrites Stem, Progenitor Cells, etc, with Cancer programming then disappears. Eventually the right micro-environment happens and the infected repgrogrammed cells wake up and begin tumors. So often researchers look for viral traces, do not find them, then discard the consideration of viruses causing cancer. This single flawed research conclusion misdirects science off target. Once we understand and accept that this Hit, Reprogram & Run ability of the Virus to cause cancer, then it disappears with little or no trace, then this leads us to focus more on Anti-viral therapeutic treatments and especially anti-viral vaccinations to stop cancer at it’s root cause. It’s an very important point that focus on eliminating active cancer tumors is treating the symptom, not the cause. Until we focus on the cause, we are destined to repeat failure and be surprised by that fact.