Many factors contribute to Cancer, but the key catalyst (even the underlying engine) is one of many Viruses, particularly CMV, but also VZV, Epstein Barr as well as other Viruses SV-40, BK, JCV and HPV. Each cancer in our body has one to many viruses associated with it. Some key ones are HPV – Human Papilloma Virus causes Cervical, Anal, Mouth, Throat, Lung, Vaginal and Penile Cancers. Epstein Barr causes Lymphoma, JC Polyoma Virus causes Colon Cancer. Epstein Barr, HPV & CMV have all been associated with Breast Cancer, thus one reason for it’s prevalence. Now down to kids Cancer, Medulloblastoma Neuroblastoma and it’s 99% terminal twin cancer Glioblastoma. For these cancers its mainly CMV (Human Cytomegalovirus), though other viruses like SV-40, JC and BK are also capable and have been found in these tumors.
Genes are biological chemical software routines that do specific tasks in our bodies. Oncogenes are genes that have been proven to contribute to the development and growth of cancer. There are approx. 50 distinct Oncogenes known and some that are found often over expressed in Medulloblastoma are MYC , MYCN and TAG. MYC and MYCN alone cause many hallmarks of cancer. When these genes are ran, they accelerate DNA replication, they turn off programmed cell death in two ways, drives new blood vessels to the cell / tumor and more (footnote ***).
Anti-Oncogenes are genes with the ability to police Oncogenes and keep them from going out of control and causing cancer (The most common damaged Medulloblastoma Anti-oncogene is P53 also known as TP53. There are two copies of TP53 and both must be damaged for this gene to be silenced (footnotes * **). When cancer happens, a couple basic things happen:
This is my latest research of my hypothesis that viruses cause cancer. This is in presentation form and I’ve also included the link to my key research backup for all that I can back-up from medical and scientific research. Appreciate your thoughts and considerations.
Gary Elsasser “Ayden’s Dad”
Viral Cancer Hypothesis Presentation
Viral Cancer Hypothesis Backup Research
Starting off, Vitamin D is not a Vitamin, long time ago mis-namer. It’s actually a Steroid Pro-Hormone – a precursor building block to hormones and it’s unbelievably important. It acts as a molecular switch activating at least 200 target genes in our bodies, thereby regulating gene expression. And many of these are the ON switches for our immune system! I only wish I knew then, what I know now.
It’s been two years since Ayden was diagnosed and I started this research journey. Lots of dead ends. Then reading too many PubMed articles to imagine, I narrowed Ayden’s cancer to a CMV driven cancer. I finally am seeing others write-up this same conclusion. Finally the ball is gaining momentum and people are living longer due to this new course of treatment. Next up, move beyond Glioblastoma, and begin running clinical trials with Medulloblastoma, Neuroblastoma, Prostate, Lung and Breast cancer. Then we need to look at CMV and other opportunistic pathogens as drivers of late term effects of all cancer survivors.
I’ve written often about the fact that 99% of Glioblastoma and 92% of Medulloblastoma show either active CMV infections for show signs that CMV has hit and run making genetic and epigenetic changes to the tumor cells. Now researchers are testing Neuroblastoma for CMV and the latest research shows 100% of the tumors showed signs of CMV or cyclomegalovirus. This continues to reinforce that brain cancers key consistent factor is triggered by a viral infection that over expresses oncogenes and disables key anti-oncogenes thus driving these devastating cancers and leads towards opportunities for new and less devastating treatment options.
USC confirms CMV as a Cancer causing Oncovirus and drive the most common salivary cancers.
An important new study from the Laboratory for Developmental Genetics at USC has confirmed cytomegalovirus (CMV) as a cause of the most common salivary gland cancers. CMV joins a group of fewer than 10 identified oncoviruses – cancer-causing viruses – including HPV.
The findings, published online in the journal Experimental and Molecular Pathology over the weekend, are the latest in a series of studies by USC researchers that together demonstrate CMV’s role as an oncovirus, a virus that can either trigger cancer in healthy cells or exploit mutant cell weaknesses to enhance tumor formation.
Lead author Michael Melnick, professor of developmental genetics in the Ostrow School of Dentistry of USC and Co-Director of the Laboratory for Developmental Genetics, said the conclusion that CMV is an oncovirus came after rigorous study of both human salivary gland tumors and salivary glands of postnatal mice.
CMV’s classification as an oncovirus has important implications for human health. The virus, which has an extremely high prevalence in humans, can cause severe illness and death in patients with compromised immune systems and can cause birth defects if a woman is exposed to CMV for the first time while pregnant. It may also be connected to other cancers besides salivary gland cancer, Melnick added.
HCMV is found is 99%+ of Glioblastoma Brain Tumors. Researchers are now beginning to measure the level of CMV infection in the tumors as a prognostic marker for expected survival. The research shows that Low Levels of CMV in a Glioblastoma tumor correlates to survival beyond 18 months. Actively treating CMV in Glioblastoma has a direct and positive improvement in patients survival length. This issue needs further research and the same research applied to other cancers to improve their survival rates.